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[3 min read] Are alopecia patients at risk of vitamin D deficiency?

Do patients with alopecia areata have an increased prevalence of vitamin D deficiency? Alopecia areata is a hair follicle‐specific autoimmune disorder, and vitamin D deficiency has been associated with various autoimmune disorders for its immunomodulatory effects. However, studies have found an inconsistent association found between alopecia and vitamin D deficiency.

A new study published in the Journal of the European Academy of Dermatology and Venereology aimed to demonstrate the differences of the mean serum 25‐hydroxyvitamin D level and prevalence of vitamin D deficiency between alopecia areata patients and the non‐alopecia population.

Researchers analysed 14 studies including 1,255 alopecia areata subjects and 784 non‐alopecia controls. The mean serum 25‐hydroxyvitamin D level was significantly lower in alopecia subjects (−8.52 ng/dL; 95% confidential interval; −5.50 to −11.53).

The alopecia subjects had higher odds of vitamin D deficiency (odds ratio of 3.89; 2.02 to 7.49, mean prevalence of 73.8%; 59.1 to 84.6%). However, researchers found it difficult to find clear correlation between serum 25‐hydroxyvitamin D level and extent of hair loss in alopecia subjects.

The study concluded that patients with alopecia areata have lower serum 25‐hydroxyvitamin D levels, and that vitamin D deficiency is highly prevalent compared to people who do not have alopecia.

It recommended that clinicians treating patients with alopecia areata should assess for vitamin D deficiency. Nutritional supplementation of vitamin D or topical vitamin D analogues can be considered for alopecia patients with vitamin D deficiency.

Read more recent research on alopecia.


Lee, S. , Kim, B. , Lee, C. and Lee, W. (2018), Increased prevalence of vitamin D deficiency in patients with alopecia areata: a systematic review and meta‐analysis. J Eur Acad Dermatol Venereol, 32: 1214-1221. doi:10.1111/jdv.14987

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One comment on “[3 min read] Are alopecia patients at risk of vitamin D deficiency?

  1. The American Journal of Clinical Nutrition published the results
    of the study showing that vitamin D (1100 IU each day) coupled with
    calcium (1400 to 1500 mg each day) ‘substantially reduces all-cancer risk in postmenopausal women. It is critical
    for ladies to improve the intake of the foods mentioned
    above in way of life so as to take care of the balanced secretion of hormones and make your body healthy.
    To live a proper life’s hard for most of the people as this entails sticking to a nutritious diet and healthy lifestyle.

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