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Is an exercise regimen combined with compression more effective at treating venous leg ulcers than just compression alone? Exercise is recommended as an adjuvant treatment for venous leg ulceration to improve calf muscle pump function. However, the association of exercise with leg ulcer healing has not been properly aggregated, and the effectiveness of different exercise interventions has not been characterised. Continue reading “[3 min read] Venous leg ulcers: exercise with compression vs compression alone”
Plane warts are a common therapeutic problem. A study published in the International Journal of Dermatology sought to assess the efficacy and safety of oral versus topical isotretinoin in the treatment of plane warts. Continue reading “Oral vs Topical Isotretinoin in the Treatment of Plane Warts”
Patient education about the importance of controlling inflammation is vital to effectively managing psoriatic arthritis, according to a review published in the New England Journal of Medicine.
The review discusses the epidemiological and clinical features, pathophysical characteristics, and available pharmacotherapies for psoriatic arthritis.
Psoriatic arthritis occurs in up to 30 percent of people with psoriasis and can have serious debilitating effects on the peripheral joints, spine, tendon insertions, and fingers. Management has improved, but complete disease control is not yet achievable. Continue reading “Managing Psoriatic Arthritis”
As part of the Royal Australasian College of Physicians’ EVOLVE initiative, the New Zealand Dermatological Society has produced five recommendations concerning oral antifungal therapy, sentinel lymph node biopsies, Mohs micrographic surgery, antibiotics for atopic dermatitis, and topical antibiotics for surgical wounds. The recommendations were recently published in the Dermatology Practice Review. Continue reading “New Recommendations In Dermatology & Skin Cancer”
Recent research has developed an effective treatment for common warts. A study recently published in the Journal of the European Academy of Dermatology and Venereology found that a combination of two compounds achieved a significant wart reduction within seven days.
DNA viruses such as HPV rely on K+ influx for replication. Both digoxin and furosemide inhibit the K+ influx by interacting with cell membrane ion co-transporters. Researchers hypothesised that these two compounds in a topical formulation may treat HPV-induced warts. They dubbed this approach Ionic Contra-Viral Therapy. Continue reading “New Treatment for Common Warts”
Mucus secretion from slugs is being developed as an adhesive for wound healing. Researchers from the Department of Bioengineering at London’s Imperial College have found that, when threatened, the Dusky Arion slug secretes a mucus that glues the creature in place, making it harder for predators to remove the slug from a surface.
The defensive mucus’ adhesive properties allow the slug to stick to a variety of wet surfaces due to a tough, cohesive polymer network. The mucus can also transfer and dissipate stress.
At an evening symposium recently held in Sydney, Dr Michael A. Ueberall gave a presentation about the management of chronic pain with opioids, with a focus on the chronic low back pain. Dr Ueberall is Vice President of the German Pain Association and pain specialist at the Institute for Neurological Sciences in Nürnberg, Germany.
Dr Ueberall’s talk highlighted the definitive place that opioid analgesics still hold in the treatment of chronic non-malignant pain. He advised, however, that opioid therapy should always be utilised as part of a multimodal treatment approach that encompasses other pharmacological and non-pharmacological measures.
Approximately two-thirds of patients with chronic non-malignant pain will experience improvements in pain, pain-related disability in daily life, and quality of life, if they undertake a multimodal treatment method that includes opioids.
However, around 50 to 70 percent of opioid-treated patients also experience constipation as a direct side effect. It is a frequent and distressing complication of potent opioid analgesic therapy. Opioid-induced bowel dysfunction (OIBD) may develop as a comorbidity in patients with chronic non-malignant pain, and may negate the success of treatment regarding pain, functionality, and quality of life. Conventional treatments of OIBD, such as laxatives, are often prescribed despite limited evidence of efficacy.
Dr Ueberall asserted that opioid analgesics are effective in the treatment of refractory neuropathic pain, but are often not recommended because of their adverse side-effects (such as constipation) and safety considerations. He proposed that safety can be improved if opioids are carefully titrated as part of a multimodal strategy to meet the needs of individual patients.
(2017) Prescribing opioids — balancing efficacy and tolerability when treating patients with chronic noncancer pain. Research Review (Speaker Series). Geelong, Victoria, Australia.
Interested in Clinical Procedures?
The HealthCert certificate courses and advanced workshops of clinical procedures offer hands-on training in various procedures, including general surgical techniques, joint injections, non-scalpel vasectomy and intrauterine systems.
Duloxetine is an effective relief for chronic back pain and the associated depressive symptoms experienced by pain sufferers, according to a recent analysis.
Patients with chronic low back pain commonly experience comorbid depression and depressive symptoms. A post hoc path analysis of clinical studies sought to assess the direct analgesic effect of duloxetine for chronic low back pain, and how it might also remedy associated depression.
If you struggle with treating ingrown toenails effectively, watch this short video interview with Dr Murphy. The experienced GP shares his very unique technique for how to treat ingrown toenails. Continue reading “An Alternative Method to Treat Ingrown Toenails”