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Despite being regarded as an easy-to-treat disease, gout diagnosis and management can be challenging for primary care practitioners. A review published recently in the Current Medical Research and Opinion journal discussed current issues in gout management and proposed some potential solutions. Continue reading “How to manage gout in everyday clinical practice”
The efficacy and safety of biologics in the treatment of moderate to severe psoriasis have been established. However, inefficacy or unforeseen adverse events sometimes demand changing the treatment to other biologics. A study in the Journal of Dermatology examined the effectiveness of this strategy. Continue reading “Results of switching of biologics in psoriasis”
Chronic pruritus is a common skin symptom with marked impact on quality of life. Adequate treatment can be challenging for clinicians, demanding the exploration of new treatment options such as oral antidepressants. Continue reading “Oral antidepressants in patients with chronic pruritus”
Lichen planus is an inflammatory condition that causes purplish, itchy, flat-topped bumps on the skin. On mucous membranes, the condition forms lacy white patches, sometimes with painful sores. Genital or vulval lichen planus may have a disabling effect on a patient’s quality of life, and evidence-based management guidelines are lacking.
A study published in the Journal of the American Academy of Dermatology reviewed the clinical presentation and treatment of 100 patients who received a diagnosis of vulval lichen planus between January 1997 and December 2015 at Mayo Clinic, USA.
What is the prevalence of allergic contact dermatitis as a reaction to sunscreen chemicals? Previous studies have found that allergic contact dermatitis to sunscreen is rare, although irritant reactions are more common, with reactions to excipients in sunscreens occurring twice as frequently as reactions to sunscreen actives. Continue reading “Allergic contact dermatitis to sunscreen”
The relevance of phototherapy in current dermatology practice was discussed at the 2018 Dermcoll, the 51st Annual Scientific Meeting of the Australasian College of Dermatologists, which was held in May on the Gold Coast, Queensland. Continue reading “Relevance of Phototherapy in Dermatology Practice”
What electrocardiographic (ECG) changes are associated with hidradenitis suppurativa? Hidradenitis suppurativa is a chronic, inflammatory skin disease, recently associated with metabolic syndrome, sub-clinical atherosclerosis and increased risk of cardiovascular disease. Continue reading “What ECG changes are associated with hidradenitis suppurativa?”
A study sought to determine the impact of dupilumab on rates of skin and other infections in patients with moderate to severe atopic dermatitis.
Atopic dermatitis is characterised by skin barrier defects, T helper type 2 cell activation, and increased risk for cutaneous and extracutaneous infections. In clinical trials, dupilumab appeared to decrease rates of skin infections in atopic dermatitis. Continue reading “Dupilumab for Atopic Dermatitis”
Plane warts are a common therapeutic problem. A study published in the International Journal of Dermatology sought to assess the efficacy and safety of oral versus topical isotretinoin in the treatment of plane warts. Continue reading “Oral vs Topical Isotretinoin in the Treatment of Plane Warts”
Patients with severe alopecia areata and vitiligo, along with their treating physicians, have been frustrated by the lack of effective therapies for these two common disorders. Both alopecia areata and vitiligo affect one to two per cent of the population and both have marked negative impacts on quality of life. Further, atopic dermatitis affects up to 20 per cent of infants and three per cent of adults. Some patients with atopic dermatitis have poorly controlled disease. A recent article highlighted the use of JAK-inhibitors in treating these conditions. Continue reading “JAK-Inhibitors for Alopecia, Vitiligo and Atopic Dermatitis”