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The study compared the risk of cardiovascular disease and diabetes for adult patients with and without atopic dermatitis by searching the PubMed, Embase and Web of Science databases. Overall, 16 publications were included in the analysis.
No association was observed between atopic dermatitis and unspecified but suspected type 2 diabetes, hypertension, stroke or myocardial infarction, but a positive association was observed with angina pectoris.
The study concluded that, while adults with atopic dermatitis in some populations have an increased prevalence of cardiovascular risk factors, such as obesity and smoking, it is unlikely that atopic dermatitis represents an independent and clinically relevant risk factor for cardiometabolic disease.
Thyssen, J. , Halling‐Overgaard, A. , Andersen, Y. , Gislason, G. , Skov, L. and Egeberg, A. (2018), The association with cardiovascular disease and type 2 diabetes in adults with atopic dermatitis: a systematic review and meta‐analysis. Br J Dermatol, 178: 1272-1279. doi:10.1111/bjd.16215
Interested in General Dermatology?
The HealthCert Professional Diploma of General Dermatology will teach you how to manage all major dermatological conditions in primary care. The courses are university quality-assured, CPD-accredited and count towards multiple Master degree pathways and clinical attachment programs in Australia and overseas. The program is delivered online.
Managing alopecia areata and androgenetic alopecia is often challenging as patients may be resistant to treatments that are currently available. The use of stem cells may be a novel option for resistant cases. A study looked at the safety and efficacy of the use of autologous bone marrow derived mononuclear cells (including stem cells) as compared to follicular stems cells for the management of resistant cases of alopecia areata and androgenetic alopecia. Continue reading “[3 min read] Stem cells for the treatment of alopecia”
Do you find treatment challenging for frontal fibrosing alopecia? Its treatment regimen often mirrors other lymphocytic‐predominant cicatricial alopecia. 5‐alpha‐reductase inhibitor has been reported with some treatment success in severe cases of frontal fibrosing alopecia, so researchers recently carried out an analysis of articles published on treatment efficacy and safety of 5‐alpha‐reductase inhibitor for the treatment of the hair loss condition. Continue reading “Alopecia: 5‐alpha‐reductase inhibitor treatment”
The most widely used topical agents for the field-based treatment of multiple actinic keratoses are 5-fluorouracil and imiquimod. Their comparative effectiveness was assessed in a real-world community-based cohort study published in the Journal of the American Academy of Dermatology.
The study compared the effectiveness of 5-fluorouracil and imiquimod in reducing risk for subsequent actinic keratoses. It identified 5,700 adults in the US who had an actinic keratosis diagnosed in 2007 and who subsequently filled a prescription for 5-fluorouracil or imiquimod. Researchers followed subjects for subsequent actinic keratoses and estimated the two-year (short-term) and five-year (long-term) differences in cumulative risk.
Pityriasis rosea is a skin rash that sometimes begins as a large spot on the chest, abdomen or back, followed by a pattern of smaller lesions. It is a self-limiting exanthematous disease associated with human herpesvirus (HHV)-6 and/or HHV-7 reactivation. In pregnant women, the condition may be associated with pregnancy complications. Continue reading “Pityriasis rosea during pegnancy”
Are adults with atopic dermatitis (eczema) at an increased risk of cardiovascular disease? A matched cohort study undertaken in the UK looked at this topic, and also investigated whether the risk varies by eczema severity and condition activity over time. Continue reading “Are eczema patients at an increased risk of cardiovascular disease?”
Despite being regarded as an easy-to-treat disease, gout diagnosis and management can be challenging for primary care practitioners. A review published recently in the Current Medical Research and Opinion journal discussed current issues in gout management and proposed some potential solutions. Continue reading “How to manage gout in everyday clinical practice”
The efficacy and safety of biologics in the treatment of moderate to severe psoriasis have been established. However, inefficacy or unforeseen adverse events sometimes demand changing the treatment to other biologics. A study in the Journal of Dermatology examined the effectiveness of this strategy. Continue reading “Results of switching of biologics in psoriasis”
Chronic pruritus is a common skin symptom with marked impact on quality of life. Adequate treatment can be challenging for clinicians, demanding the exploration of new treatment options such as oral antidepressants. Continue reading “Oral antidepressants in patients with chronic pruritus”
Lichen planus is an inflammatory condition that causes purplish, itchy, flat-topped bumps on the skin. On mucous membranes, the condition forms lacy white patches, sometimes with painful sores. Genital or vulval lichen planus may have a disabling effect on a patient’s quality of life, and evidence-based management guidelines are lacking.
A study published in the Journal of the American Academy of Dermatology reviewed the clinical presentation and treatment of 100 patients who received a diagnosis of vulval lichen planus between January 1997 and December 2015 at Mayo Clinic, USA.